Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 14, Issue 4, 2012; Page No.(597-602)

PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITY OF DOLICHANDRONE FALCATA LEAF ON SOME MDR BACTERIAL SPECIES

M.E. KISHORE AND A.S. BAGWAN

Abstract

The antibacterial properties of the plant leaf extract of Dolichandrone falcata (vernacular name: Medhshingi) has been successfully tested on some bacterial species which were of multidrug resistant (MDR). The leaf extract shows very promising results. The aqueous, acetone and ethanol extracts of plant leaves were prepared and evaluated for its phytochemical properties and antimicrobial activities. The phytochemical analysis of the preparation revealed the presence of some secondary metabolites which includes: tannins, flavanoids, glycosides, steroids, saponins and alkaloids. The in vitro antimicrobial activity of the crude aqueous, acetone and ethanol extract of the Dolichandrone falcata were investigated. The extract showed antimicrobial activities against the test organisms with different zones of inhibition. The minimum inhibitory concentration (MIC) of the ethanol extract was between 10- 20 mg/mL. The ability of the crude extracts of Dolichandrone falcata to inhibit the growth of microbes is an indication of its antimicrobial potential, which may be employed in management of microbial infections.

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