Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 9, Issue 3, 2007; Page No.(599-602)

EVALUATION OF DIURETW ACTIVITY OF SELECTED PLANTS OF THE FAM1UY CAESALVINIACEAE

AVERINENI RAVI KUMAR, K.M. SUBBU RATI-IINAM AND G. PRABAKAR

Abstract

Methanolic extracts of three species of plants belong to the family Caesalpiniaceae were evaluated for its diuretic potentials in albino rats. The parameters studied to evaluate the diuretic potentials are total urine volume, concentration of electrolytes such as sodium (Na), potassium (K+) and chloride (Cl). A diuretic activity of 1.55, 1.86, 2.33 and 1.88 was observed in frusemide, P. pterocarpum, C. racemosa and B. purpurea respectively. Good diuretic activity was evident till the fifth hour when rats were orally administrated with these plant extracts. The diuretic activity of the three plant extracts were compared with that of the standard drug frusemide at a dose of 150 mg/kg body weight. Maximum diuresis was observed in C. racemosa at the first hour of study indicated its rapid onset of diuretic action.

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