ANTIBACTERIAL ACTIVITY OF MAJOR SECONDARY METABOLITES FOUND IN FOUR SPECIES OF EDIBLE GREEN MACROALGAE GENUS CAULERPACHARLES SANTITANARAJU VAIRAPPANAbstract Major secondary metabolites in four members of green macroalgae genus Caulerpa, C. lentilifera, C. racemosa, C. microphysa and C. sertularoides, were investigated. Crude methanolic extract of these algae yield two secondary metabolites; (i) caulerpin (1), and (ii) p17,7tot (2), in various concentrations. Isolated compounds were identified based on spectroscopic data such as 1H-NMR, "C-NMR, optical rotation value, LREIMS and HREIMS data. C. lentilifera gave 15% caulerpin and 14% phytol; C. racemosa gave 5% caulerpin and 4% phytol, C. microphysa gave 2% caulerpin and 8% phytol, and C. sertularoides gave 8% caulerpin and 20% phytol. Caulerpin (1) showed moderate antibacterial activity against 8 species of bacterial isolated from algal surface.
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