Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 11, Issue 4, 2009; Page No.(923-925 )

IN VITRO STUDIES OF ANTHELMINTIC ACTIVITY OF LAGENARIA SICERARIA

S.L. DEORE, S.S.KHADABADI, K.P. CHITTAM, B.A. BAVISKAR N.D. MATKE, A.R. TODKAR, M.S. KUBADE AND K.V. MOON

Abstract

Ethanol and aqueous extracts from the fruits of L. siceraria were investigated for their anthelmintic activity against Pheretima posthuma and Ascardia galli. Various concentrations (25, 50, 100mg/mL) of aqueous and ethanolic extracts were tested in the bioassay, which involved determination of time of paralysis and time of death of the worms. Both the extracts exhibited significant anthelmintic activity at highest concentration of 100 mg/mL. Piperazine citrate was included as standard reference and distilled water as control.

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