Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 20, Dec. Suppl. No.2, 2018; Page No.(272-276)

ALLIUM SATIVUM: A SUBSTITUTE TO CHLORHEXIDINE IN DENTAL HYGIENE?

MRUDGANDHA PURANDARE, PADMAJA ANANTH SHENOY, SALEEMULLA KHAN, RENUKA ANEGUNDI, SHASHIDHAR VISHWANATH AND KIRAN CHAWLA

Abstract

Dental hygiene is essential for general health and well-being of life. Garlic (Allium sativum) which is being used as a flavoring agent, is known to have antibacterial, antiviral and antifungal activity. A study was conducted to determine the antimicrobial activity of an alcoholic extract and standardized juice of Allium sativum on different periodontal pathogens such as Streptococcus mutans, Porphyromonas gingivalis, Prevotella bivia, Fusobacterium nucleatum and Candida albicans. The fresh juice and ethanolic extract of garlic were prepared and divided in to various concentrations (20%, 40%, 60% and 80%). The standardization of fresh garlic juice was carried out by High Performance Thin Layer Chromatography (HPTLC). The antimicrobial activity was determined against periodontal isolates by agar well and disc diffusion method as per standard guidelines. The fresh garlic juice showed excellent antibacterial and antifungal activity in our study by agar well diffusion method and results were better than chlorhexidine control. Hence fresh garlic juice may be used as an alternative for chlorhexidine in dental diseases.

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