Sanaa Rahman Oleiwi
Abstract
Pantoea agglomerans is firstly a plant epiphyte frequently established in various ecological niches, such as soil, aquatic habitats or sediments and food. Four isolates of P. agglomerans (4 %) were collected from drinking water samples that were obtained from various sites in Baghdad. Investigation of P. agglomerans LPS activity as inducer of DNA fragmentation and its role as antibacterial also anti adhesion agent were studied in the present study. Results of current study revealed that LPS of P. agglomerans have an effect on DNA fragmentation of human lymphocyte cells, this effect depends on concentration and exposure time, that suggest the possibility of P. agglomerans LPS to play a role as apoptosis inducer, that may make it as anticancer agent. The results showed that LPS inhibit the bacterial growth of the tested isolates (Aeromonas hydrophila, Rahnella aquatilis, Stenotrophomonas maltophilia and Burkholderia cepacia) with a range of inhibition zone between (15-25) mm. The recent results reported the anti adhesion ability of P.agglomerans LPS on three different abiotic surfaces, this effect have significant values in cases of polystyrene and glass but not significant value in case of galvanized iron.