A.S. Kadbhane, S.B. Dahikar, S. Bhutada and P.S. Rayate
Abstract
Skin infections pose a significant health challenge globally, with the prevalence of bacterial pathogens in infected wounds and skin lesions representing a critical area of concern. This research undertakes a comprehensive investigation into the bacterial species isolated from individuals with skin infections, shedding light on their prevalence and clinical implications. A Total 133 samples were collected from infected skin. Our findings reveal a dynamic landscape of bacterial pathogens, with Staphylococcus aureus, Streptococcus pyogenes, and Pseudomonas aeruginosa emerging as predominant species. Notably, our results showcase variations in bacterial prevalence among different patient groups, underscoring the importance of tailored therapeutic approaches. From 133 samples 187 isolates were recorded on selective medium. We found 9 types of bacteria from 187 isolates of wound samples, where 34.22% were gram-positive bacteria (n = 64), 65.77% were gram-negative bacteria (n = 123), and 0.016% were no growth (n = 3). Among gram-negative samples, 4 types of bacteria were detected: Pseudomonas Spp (n = 56) 45.56%, Klebsiella Spp (n = 29) 23.57%, Proteus Spp (n =18 ) 14.63%, E. coli (n = 11) 8.94% Acinetobacter spp (n = 9)7.31%. Gram positive isolates contained only four types of bacteria; Staphylococcus Spp (n = 41) 64.06%, Enterococcus spp (n=9) 14.06%, Streptococcus spp (n=11) 17.18% and actinomycetes (n = 03) (4.68%). Pseudomonas spp. was the most predominant among the gram-negative bacteria and Staphylococcus spp. for gram-positive bacteria. In conclusion, this research elucidates the prevalence and diversity of bacterial pathogens in infected wounds, skin lesions, and skin-infected patients. By leveraging advanced methodologies and incorporating a diverse study population, our findings offer valuable insights that can inform clinical practices and guide further research in the dynamic field of dermatological microbiology. This study contributes to the ongoing discourse on skin infections, fostering a deeper understanding of the microbial landscape and paving the way for targeted interventions to enhance patient outcomes.