Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper


Vol.13, Issue 1, 2011

Page Number: 75-79

ANALYSIS OF CADMIUM IN CANCEROUS WISTAR RATS BY FLAME ATOMIC ABSORPTION SPECTROMETRY (FAAS)

G. REVATHI, P. SUVARNALATHA DEVI, N.D. PRASANNA, P. JAYALAKSHMI, S.K. SHAHEEN AND B.R. NAIK

Abstract

Cadmium is a heavy metal which occurs in the nature in the form of various inorganic compounds and as complexes along with naturally occurring chelating agents. Heavy metals which are released by industries are immutable and non- biodegradable in nature. Among them, Cadmium is one of the heavy metal which is used extensively in batteries, coating, electroplating and alloys. Although some cadmiumcontaining products can be recycled, a large share of the general cadmium pollution is caused by dumping and incineration of cadmium containing wastes. Cadmium is not only industrial pollutant but also found in ores with zinc, copper, and lead. 120 Male Wistar rats and divided in to two groups 10 animals as control Wistar rats (CWR) and the other 110 animals as cadmium chloride induced rats (CDIR) . CWR group rats were received normal saline and the CDIR group received cadmium chloride (10μM). After administration of 10 doses in 10 weeks, i.e, the total dose of the cadmium chloride reaches to 100μM. After 10 injections of cadmium chloride the tissues were collected by sacrificing the animal by cervical dislocation procedure and the cadmium concentration was estimated by using the Flame Atomic Absorption Spectrometry and it was observed in the order of Kidney>Testis>Pancreas> Spleen> Liver.

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