N. ABIRAMII, V. SHANMUCA RAIU, K. RAJATHI AND A. MAHALAKSHMI PRIYA
Abstract
The aqueous and ethanolic extract of Asteracantha longifolia and Andrographis paniculata was subjected to antibacterial screening using clinical isolates of Escherichia coil, Staphylococcus aureus, Salmonella typhimurium, Klebsiella aeruginosa, Pseudomonas aeruginosa, Yersinia entercolitica, Streptococcus pyrogens, Klebsiella pneurtioniae, Bacillus lentils, Bacillus subtilis and Bacillus cereus.Minimum inhibitory concentration of the extract was performed by broth dilution technique against the bacterial strains. The ethanolic extract of both the plants Asteracantha longifolia and Andrographis paniculata showed the maximal antibacterial activity and the chemical constituents present in the leaf ethanolic extract of the plants were analysed by GC-MS. The present study indicates the potential usefulness of Asteracantha longifolia and Andrographis pan iculata in the treatment of various pathogenic diseases.