ACETYLCHOLINE RECEPTORS AND THEIR RFGULATORY MECHANISMSMAHIRA PRAVEENAbstract Acetylcholine receptor (mAChR) molecular subtype, m2 has been postulated to be the presynaptic cholinergic autoreceptor in many brain regions. Presynaptic muscarinic autoreceptors that inhibit the release of acetylcholine play a key role in the modulation of cholinergic transmission in the peripheral and central nervous system. The mechanism for choline uptake by the brain is saturated at high concentrations of choline in the blood.
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