ASSESSMENT OF TOXICITY AND MICROBIAL ATTRIBUTES OF SYNTHETIC EPOXY RESIN AND ACETAMINOPHEN EFFLUENTSYEKEEN TAOFEEK A., AYANDELE, ABIODUN A., AKINBORO, AKEEM., ONIPEDE, ABIODUN Y. AND ALAWODE, RANMILOWOAbstract Industrial and pharmaceutical processes generate wastes and are discharged into the environment resulting to pollution which has been a source of concern due to associated health risk. Physicochemical properties and cytogenotoxicity of Epoxy Resin (ERE) and a pharmaceutical (Acetaminophen, AME) effluents were evaluated. The resistance patterns of the isolated bacteria and fungi to common antibiotic and antifungal agents were tested. Genotoxicity was measured using Allium cepa assay and dividing cells were scored for aberrations at 48 h, while growth inhibition was measured at 72 h. Physico-chemical analysis showed variations between the effluents. Microbial load of 3.26 × 10 9 cfu/mL and 6.9 × 10 9 cfu/mL for bacteria, 18.5 × 10 9 cfu/mL and 1.6 × 10 7 cfu/mL for fungi were obtained for ERE and AME, respectively. Isolated bacteria included Bacillus megaterium, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Bacillus licheniformis andPseudomonas putida.The multiple drug resistance patterns of 3-10 and 4-7 antibiotics were observed for ERE and AME, respectively. Significant reductions in root lengths at 2.5, 5.0 and 10.0%, and decreased mitotic index (except 1.0% ERE) were observed in both effluents. Aberrations observed included laggard chromosome, sticky, and fragmentation. The evaluated effluents are cytotoxic and have potential of promoting resistant strains of microorganisms.
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